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首頁(yè)> 中文期刊> 《磁共振成像》 >MR擴(kuò)散加權(quán)成像表觀擴(kuò)散系數(shù)與乳腺浸潤(rùn)性導(dǎo)管癌病理分級(jí)相關(guān)性研究

MR擴(kuò)散加權(quán)成像表觀擴(kuò)散系數(shù)與乳腺浸潤(rùn)性導(dǎo)管癌病理分級(jí)相關(guān)性研究

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摘要

目的：探討表觀擴(kuò)散系數(shù)(apparent diffusion coefficient，ADC)值與乳腺癌病理分級(jí)是否具有相關(guān)性。材料與方法回顧性分析經(jīng)病理證實(shí)并具有病理分級(jí)的66例乳腺浸潤(rùn)性導(dǎo)管癌，對(duì)病灶進(jìn)行ADC值測(cè)量，取感興趣區(qū)的ADC均值A(chǔ)DCmean及最小值A(chǔ)DCmin。依據(jù)治療及預(yù)后(病理分級(jí)、淋巴結(jié)情況)分為病理分級(jí)、預(yù)后復(fù)發(fā)兩組，采用SPSS19.0(One-way ANOVA、LSD檢驗(yàn)、Spearman等級(jí)秩相關(guān))進(jìn)行統(tǒng)計(jì)學(xué)分析。結(jié)果 ADCmean值在病理分級(jí)1、2、3組內(nèi)均數(shù)分別為0.993×10-3 mm2/s、0.969×10-3 mm2/s、0.926×10-3 mm2/s，ADCmin值的均數(shù)分別為0.849×10-3 mm2/s、0.660×10-3 mm2/s、0.535×10-3 mm2/s。ADCmean值在預(yù)后復(fù)發(fā)A、B、C組內(nèi)均數(shù)分別為1.014×10-3 mm2/s、1.029×10-3 mm2/s、0.919×10-3 mm2/s， ADCmin值的均數(shù)分別為0.918×10-3 mm2/s、0.750×10-3 mm2/s、0.540×10-3 mm2/s。 ADCmean與病理分級(jí)、預(yù)后復(fù)發(fā)分組間不具有相關(guān)性，ADCmin與病理分級(jí)組(r=-0.615，P=0.000)、預(yù)后復(fù)發(fā)組(r=-0.754，P=0.000)間呈負(fù)相關(guān)。結(jié)論 ADCmin值可以作為對(duì)乳腺癌術(shù)前治療方案的制定及預(yù)后復(fù)發(fā)進(jìn)行初步評(píng)估的一種指標(biāo)。%AbstractObjectives:The aim of this study was to evaluate the correlation between apparent diffusion coefficient (ADC) values and histopathologic classification of breast invasive ductal cancer.Materials and Methods:Sixty-six cases of breast cancer conformed by histopathology with histopathologic classiifcation were involved in this retrospective study. The ADC values of lesions were measured and the mean (ADCmean) and minimum (ADCmin) of regions of interest (ROIs) were taken. The cases were divided into two groups, histopathologic classification and prognostic recurrence, according to the treatment and prognosis (histopathologic classification, lymph node status). The correlation was analyzed by using SPSS19.0 software (one-way ANOVA, LSD test andSpearman’ rank correlation coefifcient method).Results:There were two groups, histopathologic classiifcation group and prognostic recurrence group, which were divided three stages, respectively. ADCmean were 0.993×10-3 mm2/s、0.969×10-3mm2/s、0.926×10-3mm2/s, respectively, whileADCmin were0.849×10-3 mm2/s、0.660×10-3 mm2/s、0.535×10-3 mm2/s in the former group, respectively, ADCmean were1.014×10-3 mm2/s、1.029×10-3 mm2/s、0.919×10-3 mm2/s, respectively, while ADCmin were 0.918×10-3 mm2/s、0.750×10-3 mm2/s、0.540×10-3 mm2/s in the latter group, respectively. ADCmean had no correlation with either histopathologic classification group or prognostic recurrence group. There was negative correlation between ADCmin and histopathologic classification group (r=-0.615,P=0.000) as well as prognostic recurrence group (r=-0.754,P=0.000).Conclusions:The ADCmin can be considered as an indicator of the development of medical plan before breast cancer surgery and the preliminary assessment of prognostic recurrence.

著錄項(xiàng)

  • 來(lái)源
    《磁共振成像》 |2015年第2期|131-135|共5頁(yè)
  • 作者單位

    廣西醫(yī)科大學(xué)附屬腫瘤醫(yī)院影像中心;

    南寧 530021;

    廣西醫(yī)科大學(xué)附屬腫瘤醫(yī)院影像中心;

    南寧 530021;

    廣西醫(yī)科大學(xué)附屬腫瘤醫(yī)院影像中心;

    南寧 530021;

    廣西醫(yī)科大學(xué)附屬腫瘤醫(yī)院影像中心;

    南寧 530021;

    廣西醫(yī)科大學(xué)附屬腫瘤醫(yī)院影像中心;

    南寧 530021;

    廣西醫(yī)科大學(xué)附屬腫瘤醫(yī)院影像中心;

    南寧 530021;

    廣西醫(yī)科大學(xué)附屬腫瘤醫(yī)院影像中心;

    南寧 530021;

    廣西醫(yī)科大學(xué)附屬腫瘤醫(yī)院影像中心;

    南寧 530021;

  • 原文格式 PDF
  • 正文語(yǔ)種 chi
  • 中圖分類 核磁共振成像;乳腺腫瘤;
  • 關(guān)鍵詞

    乳腺癌; 病理分級(jí); 表觀擴(kuò)散系數(shù);

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