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Spectrum and antibiotic resistance of catheter-associated urinary tract infections

機譯：導管相關(guān)性尿路感染的頻譜和抗生素耐藥性

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摘要

Catheter associated urinary tract infections (CAUTIs) are amongst the most common nosocomial infections and are also considered among the most common complications associated with indwelling urinary catheters. Most catheter associated infections are derived from the patient’s own perineal flora, however the presence of a catheter increases the chance of being colonised by cross transmission of nosocomial bacteria as well. Most episodes of short-term catheter-associated bacteriuria are asymptomatic and are caused by single organisms, while long-term catheterisation promotes multibacterial infections and colonization. With prolonged duration of catheterization bacteriuria is considered universal because of the formation of biofilms on the surface of the catheter. Chronic indwelling catheters are an important reservoir of different multiresistant gram-negative organisms, therefore they are frequently isolated from CAUTIs. Treatment of catheter associated asymptomatic bacteriuria is not recommended because it will only promote the emergence of resistant organisms without effectively clearing the urine of catheterised patients.
機譯：導管相關(guān)的尿路感染（CAUTI）是最常見的醫(yī)院感染之一，也被認為是與導尿管留置相關(guān)的最常見并發(fā)癥。大多數(shù)與導管相關(guān)的感染均來自患者自身的會陰菌群，但是導管的存在也增加了醫(yī)院細菌交叉?zhèn)鞑ザň拥臋C會。短期導管相關(guān)菌尿的大多數(shù)發(fā)作是無癥狀的，并且是由單個生物體引起的，而長期導管插入術(shù)則促進了多細菌感染和定植。隨著導管插入時間的延長，細菌尿被認為是普遍的，因為在導管表面上形成了生物膜。慢性留置導管是不同的多重耐藥革蘭氏陰性生物的重要儲存庫，因此它們經(jīng)常與CAUTI隔離。不建議治療與導管相關(guān)的無癥狀菌尿，因為它只會促進耐藥菌的出現(xiàn)，而不能有效清除導管患者的尿液。

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