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Noise-bias and polarization-artifact corrected optical coherence tomography by maximum a-posteriori intensity estimation

機(jī)譯：通過(guò)最大后驗(yàn)強(qiáng)度估計(jì)對(duì)噪聲偏向和偏振偽像校正的光學(xué)相干斷層掃描

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摘要

We propose using maximum a-posteriori (MAP) estimation to improve the image signal-to-noise ratio (SNR) in polarization diversity (PD) optical coherence tomography. PD-detection removes polarization artifacts, which are common when imaging highly birefringent tissue or when using a flexible fiber catheter. However, dividing the probe power to two polarization detection channels inevitably reduces the SNR. Applying MAP estimation to PD-OCT allows for the removal of polarization artifacts while maintaining and improving image SNR. The effectiveness of the MAP-PD method is evaluated by comparing it with MAP-non-PD, intensity averaged PD, and intensity averaged non-PD methods. Evaluation was conducted in vivo with human eyes. The MAP-PD method is found to be optimal, demonstrating high SNR and artifact suppression, especially for highly birefringent tissue, such as the peripapillary sclera. The MAP-PD based attenuation coefficient image also shows better differentiation of attenuation levels than non-MAP attenuation images.
機(jī)譯：我們建議使用最大后驗(yàn)（MAP）估計(jì)來(lái)提高偏振分集（PD）光學(xué)相干斷層掃描中的圖像信噪比（SNR）。 PD檢測(cè)可消除偏振偽影，當(dāng)對(duì)高度雙折射的組織成像或使用柔性纖維導(dǎo)管時(shí)，偏振偽影很常見(jiàn)。但是，將探頭功率分配給兩個(gè)極化檢測(cè)通道不可避免地會(huì)降低SNR。將MAP估計(jì)應(yīng)用于PD-OCT可以消除偏振偽影，同時(shí)保持并改善圖像SNR。通過(guò)將MAP-PD方法與MAP-non-PD方法，強(qiáng)度平均PD和強(qiáng)度平均非PD方法進(jìn)行比較來(lái)評(píng)估其有效性。用人眼在體內(nèi)進(jìn)行評(píng)估。發(fā)現(xiàn)MAP-PD方法是最佳方法，它顯示出高SNR和偽影抑制效果，尤其是對(duì)于高度雙折射的組織（如乳頭周?chē)柲ぃ?。與非MAP衰減圖像相比，基于MAP-PD的衰減系數(shù)圖像還顯示出更好的衰減級(jí)別差異。

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