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Phage on the stage

機譯：舞臺上的噬菌體

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The resurgence of interest in bacteriophages for use in combating antibiotic resistant bacteria is coincident with an urgent call for more effective science education practices, including hands-on learning opportunities. To address this issue, a number of solutions have been proposed, including a large educational experiment, begun in 2007 by the Howard Hughes Medical Institute and currently involving over 85 colleges and universities, which has students discovering unique phages, obtaining images, and purifying phage DNA. A subset of these phage genomes is sequenced and analyzed using bioinformatics tools. Papers describing individual phage discoveries and comparative genomic studies are being published regularly. The vast majority of students in the program are in their first year of college, a critical time in capturing their interest and retaining them as science majors. This viral discovery model is being adopted and modified by a wide variety of educational institutions using a number of different bacterial hosts. In the opinion of the authors, this program and others like it represent a model accessible to virtually any undergraduate setting. And because of these programs, bacteriophage enthusiasts (academics, health professionals, biotechnology companies) can look forward to more well prepared students entering their ranks and should anticipate many more potentially useful phages discovered and characterized.
機譯：對用于抵抗抗生素抗性細菌的噬菌體興趣的重新出現(xiàn)與緊迫呼吁采取更有效的科學(xué)教育實踐，包括動手學(xué)習(xí)的機會。為了解決這個問題，已提出了許多解決方案，其中包括一項由霍華德·休斯醫(yī)學(xué)院（Howard Hughes Medical Institute）于2007年開始的大型教育實驗，目前涉及85所高校，其中學(xué)生可以發(fā)現(xiàn)獨特的噬菌體，獲取圖像并純化噬菌體。脫氧核糖核酸。使用生物信息學(xué)工具對這些噬菌體基因組的一部分進行測序和分析。定期發(fā)表描述單個噬菌體發(fā)現(xiàn)和比較基因組研究的論文。該計劃中的絕大多數(shù)學(xué)生都處于大學(xué)一年級，這是吸引他們的興趣并保留他們作為理科專業(yè)的關(guān)鍵時刻。各種各樣的教育機構(gòu)正在使用許多不同的細菌宿主來采用和修改這種病毒發(fā)現(xiàn)模型。在作者看來，該程序和其他類似程序代表了幾乎任何大學(xué)生均可訪問的模型。由于有了這些計劃，噬菌體愛好者（學(xué)術(shù)界，衛(wèi)生專業(yè)人員，生物技術(shù)公司）可以期待更多準(zhǔn)備充分的學(xué)生進入他們的行列，并應(yīng)該期待發(fā)現(xiàn)和鑒定出更多潛在有用的噬菌體。

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