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首頁> 美國衛(wèi)生研究院文獻>Asian Pacific Journal of Tropical Disease >Co-infection of visceral leishmaniasis and pulmonary tuberculosis: a case study
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Co-infection of visceral leishmaniasis and pulmonary tuberculosis: a case study

機譯：內(nèi)臟利什曼病和肺結(jié)核的合并感染：一個案例研究

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Co-infection of visceral leishmaniasis and pulmonary tuberculosis are increasing public health problem in eastern region of country. A large number of clinical cases of leishmaniasis and tuberculosis have been reported in Sudan. Such type of co-infections lead to decreased host's immune system. This is a case report of 48 years old male with visceral leishmaniasis and pulmonary tuberculosis. He arrived at hospital with complaints of fever with rigor, abdominal pain, weakness, loss of appetite, yellowish discoloration of urine and sclerosis at lower back. Bone marrow aspiration cytology revealed the presence of Leishmania donovani bodies (2+). His treatment was initiated with amphotericin B deoxycholate (inj. Fungizone) 15 infusions on alternate days with 5% dextrose. He had 20 years past history of pulmonary tuberculosis. His chest X-ray showed increased bronchovascular marking encysted pleural effusion on lower segment of right lung. Ultrasonography guided fine needle aspiration cytology of pleural fluid for protein, sugar, lactate dehydrogenase, adenosine deaminase, cell type and cell count. Cytological reports confirmed pulmonary tuberculosis. Antitubercular therapy (four drug regimen: rifampicin, isoniazid, ethambutal, and pyrazinamide) was started. Co-infection of visceral leishmaniasis and pulmonary tuberculosis is a real threat in developing countries. There is a need of cost effective diagnostic and therapeutic facilities for these co-infections.
機譯：內(nèi)臟利什曼病和肺結(jié)核的共同感染正在該國東部地區(qū)增加公共衛(wèi)生問題。蘇丹已有大量臨床病例報道利什曼病和結(jié)核病。這種類型的共感染導致宿主免疫系統(tǒng)降低。這是一例內(nèi)臟利什曼病和肺結(jié)核的48歲男性病例報告。他因發(fā)燒，嚴厲的腹痛，虛弱，食欲不振，尿色變黃和下背部的硬化而入院。骨髓抽吸細胞學檢查顯示存在利什曼原蟲體（2+）。他的治療開始于每隔15天輸注兩性霉素B脫氧膽酸鹽（Fungizone）和5％葡萄糖。他有20年的肺結(jié)核病史。他的胸部X線照片顯示右肺下段支氣管血管標記增多，引起胸腔積液。超聲檢查指導胸腔積液細針穿刺細胞學檢查蛋白質(zhì)，糖，乳酸脫氫酶，腺苷脫氨酶，細胞類型和細胞計數(shù)。細胞學報告證實了肺結(jié)核。開始抗結(jié)核治療（四種藥物療法：利福平，異煙肼，乙胺丁醇和吡嗪酰胺）。內(nèi)臟利什曼病和肺結(jié)核的共同感染是發(fā)展中國家的真正威脅。需要用于這些合并感染的成本有效的診斷和治療設(shè)施。

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