Decay of HIV DNA in the Reservoir and the Impact of Short Treatment Interruption in Kenyan Infants

機譯：水庫中HIV DNA的衰減以及短期干預對肯尼亞嬰兒的影響

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We compared change in HIV reservoir DNA following continued antiretroviral therapy (ART) vs short treatment interruption (TI) in early ART-treated Kenyan infants. While HIV DNA in the reservoir decayed with continued ART, HIV DNA levels were similar to pre-TI HIV DNA reservoir levels in most children after short TI.

機譯：我們比較了接受抗逆轉錄病毒治療（ART）與早期接受ART治療的肯尼亞嬰兒短暫治療中斷（TI）后HIV儲庫DNA的變化。盡管持續(xù)進行抗逆轉錄病毒療法后，水庫中的HIV DNA衰減，但大多數(shù)TI患者在短暫接受TI后，HIV DNA的水平與TI前的HIV DNA相似。

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期刊名稱 Open Forum Infectious Diseases
作者
Mark D Pankau; Dalton Wamalwa; Sarah Benki-Nugent; Kenneth Tapia; Evelyn Ngugi; Agnes Langat; Vincent Otieno; Helen Moraa; Elizabeth Maleche-Obimbo; Julie Overbaugh; Grace C John-Stewart; Dara A Lehman;
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年(卷),期 2018(5),1
年度 2018
頁碼 ofx268
總頁數(shù) 4
原文格式 PDF
正文語種
中圖分類病毒傳染病;
關鍵詞
antiretroviral therapy HIV DNA infants reservoir treatment interruption;

機譯：抗逆轉錄病毒療法;HIV DNA;嬰兒;儲庫;治療中斷;

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專利

1. Decay of HIV DNA in the Reservoir and the Impact of Short Treatment Interruption in Kenyan Infants [J] . Mark D Pankau, Julie Overbaugh, Elizabeth Maleche-Obimbo, Open Forum Infectious Diseases . 2017,第1期

機譯：水庫中HIV DNA的衰減以及肯尼亞嬰兒短期治療中斷的影響
2. Impact of Treatment Interruption on HIV Reservoirs and Lymphocyte Subsets in Individuals Who Initiated Antiretroviral Therapy During the Early Phase of Infection [J] . Huiting Erin D., Gittens Kathleen, Justement J. Shawn, The Journal of Infectious Diseases . 2019,第2期

機譯：治療中斷對艾滋病毒儲存器和淋巴細胞亞群的影響在感染早期發(fā)起抗逆轉錄病毒治療的個體
3. A high HIV DNA level in PBMCs at antiretroviral treatment interruption predicts a shorter time to treatment resumption, independently of the CD4 nadir. [J] . Piketty C, Weiss L, Assoumou L, Journal of Medical Virology . 2010,第11期

機譯：PBMC中抗逆轉錄病毒治療中斷時HIV DNA高水平預示著恢復治療的時間較短，而與CD4最低點無關。
4. Assessing the Impact of Targeted Screening and Treatment of Diabetes and Hypertension Among Adults Living with HIV in Nairobi, Kenya [C] . Melissa Schnure, Parastu Kasaie, David Dowdy, Simulation Conference . 2020

機譯：在肯尼亞，肯尼亞患有艾滋病毒艾滋病毒的成人患有患者和高血壓治療糖尿病和高血壓的影響
5. Rebound Relationships: An Investigation of HIV-1 Rebound Dynamics and Host Immune Responses During Analytical Treatment Interruption [D] . Salantes, D. Brenda. 2018

機譯：反彈關系：分析治療中斷期間HIV-1回彈動力學和宿主免疫應答的調(diào)查
6. Impact of Treatment Interruption on HIV Reservoirs and Lymphocyte Subsets in Individuals Who Initiated Antiretroviral Therapy During the Early Phase of Infection [O] . Erin D Huiting, Kathleen Gittens, J Shawn Justement, -1

機譯：感染早期階段中啟動抗逆轉錄病毒療法的個體中治療中斷對HIV儲庫和淋巴細胞亞群的影響
7. Impact of Treatment Interruption on HIV Reservoirs and Lymphocyte Subsets in Individuals Who Initiated Antiretroviral Therapy During the Early Phase of Infection [O] . Erin D Huiting, Kathleen Gittens, J Shawn Justement, 2019

機譯：治療中斷對艾滋病毒儲存器和淋巴細胞亞群的影響在感染早期發(fā)起抗逆轉錄病毒治療的個體

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Decay of HIV DNA in the Reservoir and the Impact of Short Treatment Interruption in Kenyan Infants

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