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Time-constrained functional connectivity analysis of cortical networks underlying phonological decoding in typically developing school-aged children: A magnetoencephalography study

機(jī)譯：在典型發(fā)展學(xué)齡兒童中語音解碼潛在語音解碼的時間約束功能連通性分析：磁性腦圖研究

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The study investigated functional associations between left hemisphere occipitotemporal, temporoparietal, and inferior frontal regions during oral pseudoword reading in 58 school-aged children with typical reading skills (aged 10.4±1.6, range 7.5–12.5 years). Event-related neuromagnetic data were used to compute source-current density waveforms using a minimum norm algorithm. Temporally-constrained contributions were established for four ROIs (STG, SMG, ANG, and IFG) by controlling for the autoregressive effects of activity in each ROI. Unique contributions made by activity in one ROI to subsequent activity in a second ROI were assessed through multiple regression analyses. Forward associations between lateral (LOC) and ventral occipitotemporal cortices (fusiform gyrus) to each of the four main ROIs were also examined. The earliest significant contributions to SMG and ANG activation (at 200–250 ms) were made by preceding activity in the fusiform gyrus. The degree of activity in IFG appeared to be determined by earlier activity in ANG and STG.
機(jī)譯：該研究調(diào)查了58名具有典型閱讀技能的學(xué)齡兒童（10.4±1.6歲，范圍7.5–12.5歲）在口頭假單詞閱讀期間左半球枕顳葉，顳顳葉和額葉下部之間的功能關(guān)聯(lián)。與事件相關(guān)的神經(jīng)磁數(shù)據(jù)被用于使用最小范數(shù)算法來計算源電流密度波形。通過控制每個ROI中活動的自回歸效應(yīng)，為四個ROI（STG，SMG，ANG和IFG）建立了時間受限的貢獻(xiàn)。通過多次回歸分析評估了一個ROI中的活動對第二個ROI中的后續(xù)活動做出的獨特貢獻(xiàn)。還檢查了外側(cè)（LOC）和腹枕顳皮層（梭狀回）與四個主要ROI的正向關(guān)聯(lián)。梭形回中的先前活動對SMG和ANG激活有最早的顯著貢獻(xiàn)（在200–250 ms）。 IFG中的活性程度似乎由ANG和STG中的早期活性決定。

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