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首頁> 美國衛(wèi)生研究院文獻>Journal of Diabetes Science and Technology >Personalized Medicine for Diabetes: A Genomics Study of Type 2 Diabetes Mellitus in U.S. Air Force Personnel
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Personalized Medicine for Diabetes: A Genomics Study of Type 2 Diabetes Mellitus in U.S. Air Force Personnel

機譯:糖尿病個性化藥物:美國空軍人員2型糖尿病的基因組研究

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摘要

The military community is at high risk for type 2 diabetes (T2D), especially as it relates to military beneficiaries, although preventive measures can be implemented to reduce disease onset. This study evaluates the prevalence of risk-associated single nucleotide polymorphisms in patients diagnosed with T2D within active duty, retired military, and military-dependent populations on Lackland Air Force Base compared to nondiabetic controls. Results will be used as a basis of comparison to analyze risk-conferring genotypes in the young, healthy active duty population to generate the prevalence of T2D risk-associated factors in our current and future war fighters. Identifying genetic markers of T2D prior to abnormal glucose control and insulin resistance may ultimately adjust future risk through early detection, healthy lifestyle modifications, and disease management programs.
機譯:盡管可以采取預(yù)防措施以減少疾病發(fā)作,但是軍事界罹患2型糖尿?。═2D)的風(fēng)險很高,特別是與軍事受益人有關(guān)。這項研究評估了與非糖尿病對照組相比,在拉克蘭空軍基地現(xiàn)役,退休軍人和軍事依賴人群中被診斷為T2D的患者中,與風(fēng)險相關(guān)的單核苷酸多態(tài)性的患病率。結(jié)果將用作比較的基礎(chǔ),以分析年輕,健康的現(xiàn)役人員的風(fēng)險賦予基因型,從而在我們現(xiàn)在和將來的戰(zhàn)斗人員中普遍產(chǎn)生T2D風(fēng)險相關(guān)因素。在異常葡萄糖控制和胰島素抵抗之前鑒定T2D的遺傳標記可能最終通過早期發(fā)現(xiàn),健康的生活方式改良和疾病管理計劃來調(diào)整未來風(fēng)險。

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