A Dose-Ranging Study of Epinephrine Hydrofluroalkane Metered-Dose Inhaler (Primatene? MIST) in Subjects with Intermittent or Mild-to-Moderate Persistent Asthma

機(jī)譯：間歇性或輕度至中度持續(xù)哮喘受試者腎上腺水紅核計(jì)量吸入器（Primatene?霧）的劑量范圍研究

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摘要

Two sequential single-dose crossover dose-ranging studies were performed to evaluate the clinical efficacy and safety profile of epinephrine hydrofluroalkane (HFA) metered-dose inhaler (MDI) formulation at various doses in subjects with asthma.

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期刊名稱 Journal of Aerosol Medicine and Pulmonary Drug Delivery
作者
Edward M. Kerwin; Donald P. Tashkin; Thomas R. Murphy; George W. Bensch; Tony Marrs; Mary Z. Luo; Jack Y. Zhang;
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作者單位

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年(卷),期 -1(33),4
年度 -1
頁(yè)碼 -1
總頁(yè)數(shù) 8
原文格式 PDF
正文語(yǔ)種
中圖分類呼吸生理學(xué);
關(guān)鍵詞
asthma; dose–response; efficacy; inhaled epinephrine; metered-dose inhalers;

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1. A Dose-Ranging Study of Epinephrine Hydrofluroalkane Metered-Dose Inhaler (Primatene(R) MIST) in Subjects with Intermittent or Mild-to-Moderate Persistent Asthma [J] . Kerwin Edward M., Tashkin Donald P., Murphy Thomas R., Journal of aerosol medicine and pulmonary drug delivery . 2020,第4期

機(jī)譯：間歇性或輕度至中度持續(xù)哮喘受試者腎上腺水紅核計(jì)量吸入器（Primatene霧）的劑量范圍研究
2. Efficacy, safety, and dose response of glycopyrronium administered by metered dose inhaler using co-suspension delivery technology in subjects with intermittent or mild-to-moderate persistent asthma: A randomized controlled trial [J] . Kerwin Edward, Wachtel Andrew, Sher Lawrence, Respiratory medicine . 2018,第期

機(jī)譯：通過(guò)計(jì)量劑量吸入器在受試者中使用共懸浮遞送技術(shù)給藥的療效，安全性和劑量反應(yīng)，其具有間歇或輕度至中度持續(xù)哮喘：隨機(jī)對(duì)照試驗(yàn)
3. The effect of budesonide and formoterol in one pressurized metered-dose inhaler on patient-reported outcomes in adults with mild-to-moderate persistent asthma. [J] . Murphy K, Nelson H, Parasuraman B, Current medical research and opinion . 2008,第3期

機(jī)譯：一劑加壓計(jì)量吸入器中布地奈德和福莫特羅對(duì)成年輕度至中度持續(xù)性哮喘患者報(bào)告的結(jié)局的影響。
4. Study of a Pressurized Metered-dose Inhaler Spray Parameters in Fluent [C] . Ricardo F. Oliveira, Senhorinha Teixeira, Luis F. Silva, World Congress on Engineering . 2010

機(jī)譯：流利的加壓計(jì)量吸入?yún)?shù)的研究
5. Pharmacokinetics and tolerability (Study 1) with particular reference to ocular safety (Study 2) of tiotropium Respimat? Soft Mist? Inhaler: findings from two dose-ranging studies in healthy men [O] . Ulrich Feifel, Gudrun Wallenstein, Karl-Ludwig Rominger, 2008

機(jī)譯：噻托溴銨Respimat?Soft Mist?吸入器的藥代動(dòng)力學(xué)和耐受性（研究1）尤其是眼部安全性（研究2）：健康男性中兩項(xiàng)劑量范圍研究的結(jié)果
6. A Dose-Ranging Study of Epinephrine Hydrofluroalkane Metered-Dose Inhaler (Primatene? MIST) in Subjects with Intermittent or Mild-to-Moderate Persistent Asthma [O] . Edward M. Kerwin, Donald P. Tashkin, Thomas R. Murphy, 2020

機(jī)譯：間歇性或輕度至中度持續(xù)哮喘受試者腎上腺水紅核計(jì)量吸入器（Primatene?霧）的劑量范圍研究
7. Studies on Air Pollution: Effects of Nitrogen Dioxide on Airway Caliber and Reactivity in Asmatic Subjects; Effects of Nitrogen Dioxide on Lung Lymphocytes and Macrophage Products in Healthy Subjects; Nasal and Bronchial Effects of Sulfur Dioxide in Asthmatic Subjects [R] . Boushey, H. A. , Rubinstein, I. , Bigby, B. G. 1988

機(jī)譯：空氣污染研究：二氧化氮對(duì)軀體受試者氣道口徑和反應(yīng)性的影響;二氧化氮對(duì)健康人肺淋巴細(xì)胞和巨噬細(xì)胞產(chǎn)物的影響;哮喘患者二氧化硫的鼻腔和支氣管效應(yīng)

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A Dose-Ranging Study of Epinephrine Hydrofluroalkane Metered-Dose Inhaler (Primatene? MIST) in Subjects with Intermittent or Mild-to-Moderate Persistent Asthma

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