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首頁> 外文會議>Microfluidics, bioMEMS, and medical microsystems VII >Active integrated components for fluid control in automatic analytical chip-based systems
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Active integrated components for fluid control in automatic analytical chip-based systems

機譯:有源集成組件,用于基于自動分析芯片的系統(tǒng)中的流體控制

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A robust optical sensor for liquid control in fluidic channels is reported. The sensor operates on light intensity modulation resulting from alteration of total internal reflection into partial reflection. When a liquid guided in a channel covers an integrated prism, the total internal reflection is changed into a partial reflection, resulting in an intensity modulation of the reflected light. The set-up comprises a fibre which is built in a coupler unit with integrated LED and photodiode as well as a prism micro-machined directly into a micro-fluidic polymeric channel by laser ablation. The Prism is of 45-90-45° type with a dimension of 0.5 mm × 1 mm × 2 mm. In this design the radiation of the LED light source is transmitted and collected from the prism by a 50:50 fibre coupler by means of total or partial internal reflection. The sensor was characterised by filling alternately the channel with water and air. The influence of stray light onto the sensor signal was tested by applying a strong uncollimated illumination of the channel. Only a small increase in the output signal level in the presence of air but a strong increase in case of the presence of water could be detected.
機譯:報道了用于流體通道中液體控制的堅固的光學傳感器。傳感器對光強度進行調(diào)制,這是由于將全內(nèi)反射變?yōu)椴糠址瓷涠鸬?。當在通道中引導的液體覆蓋集成棱鏡時,全內(nèi)反射將變?yōu)椴糠址瓷?,從而導致反射光的強度調(diào)制。該裝置包括一根光纖,該光纖內(nèi)置在帶有集成LED和光電二極管的耦合器單元中,以及通過激光燒蝕直接微加工成微流體聚合物通道的棱鏡。棱鏡為45-90-45°類型,尺寸為0.5毫米×1毫米×2毫米。在這種設計中,LED光源的輻射通過50:50光纖耦合器通過全內(nèi)反射或部分內(nèi)反射從棱鏡傳輸和收集。傳感器的特征在于,將水和空氣交替填充到通道中。通過對通道施加強非準直照明來測試雜散光對傳感器信號的影響。在存在空氣的情況下,只能檢測到輸出信號電平的小幅增加,但是在存在水的情況下,可以檢測到強烈的增加。

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