国产bbaaaaa片,成年美女黄网站色视频免费,成年黄大片,а天堂中文最新一区二区三区,成人精品视频一区二区三区尤物

首頁> 美國衛(wèi)生研究院文獻>other >Multiplex Immunosensor Arrays for Electrochemical Detection of Cancer Biomarker Proteins
【2h】

Multiplex Immunosensor Arrays for Electrochemical Detection of Cancer Biomarker Proteins

機譯:電化學(xué)免疫檢測癌癥生物標志物蛋白的多重免疫傳感器陣列。

代理獲取
本網(wǎng)站僅為用戶提供外文OA文獻查詢和代理獲取服務(wù),本網(wǎng)站沒有原文。下單后我們將采用程序或人工為您竭誠獲取高質(zhì)量的原文,但由于OA文獻來源多樣且變更頻繁,仍可能出現(xiàn)獲取不到、文獻不完整或與標題不符等情況,如果獲取不到我們將提供退款服務(wù)。請知悉。

摘要

Measuring panels of protein biomarkers offer a new personalized approach to early cancer detection, disease monitoring and patients’ response to therapy. Multiplex electrochemical methods are uniquely positioned to provide faster, more sensitive, point of care (POC) devices to detect protein biomarkers for clinical diagnosis. Nanomaterials-based electrochemical methods offer sensitivity needed for early cancer detection. This review discusses recent advances in multiplex electrochemical immunosensors for cancer diagnostics and disease monitoring. Different electrochemical strategies including enzyme-based immunoarrays, nanoparticle-based immunoarrays and electrochemiluminescence methods are discussed. Many of these methods have been integrated into microfluidic systems, but measurement of more than 2–4 protein markers in a small single serum sample is still a challenge. For POC applications, a simple, low cost method is required. Major challenges in multiplexed microfluidic immunoassays are reagent additions and washing steps that require creative engineering solutions. 3-D printed microfluidics and paper-based microfluidic devices are also explored.
機譯:蛋白質(zhì)生物標記物的檢測面板為早期癌癥檢測,疾病監(jiān)測和患者對治療的反應(yīng)提供了一種新的個性化方法。多重電化學(xué)方法的獨特定位是提供更快,更靈敏的即時點(POC)設(shè)備,以檢測蛋白質(zhì)生物標志物以進行臨床診斷?;诩{米材料的電化學(xué)方法可提供早期癌癥檢測所需的靈敏度。這篇綜述討論了用于癌癥診斷和疾病監(jiān)測的多重電化學(xué)免疫傳感器的最新進展。討論了不同的電化學(xué)策略,包括基于酶的免疫陣列,基于納米顆粒的免疫陣列和電化學(xué)發(fā)光方法。這些方法中有許多已被集成到微流體系統(tǒng)中,但是在一個小的單一血清樣品中測量超過2–4個蛋白質(zhì)標記仍然是一個挑戰(zhàn)。對于POC應(yīng)用,需要一種簡單,低成本的方法。多重微流免疫分析的主要挑戰(zhàn)是試劑添加和清洗步驟,這些步驟需要創(chuàng)新的工程解決方案。還研究了3-D打印的微流體和基于紙張的微流體設(shè)備。

著錄項

相似文獻

  • 外文文獻
  • 中文文獻
  • 專利
代理獲取

客服郵箱:kefu@zhangqiaokeyan.com

京公網(wǎng)安備:11010802029741號 ICP備案號:京ICP備15016152號-6 六維聯(lián)合信息科技 (北京) 有限公司?版權(quán)所有
  • 客服微信

  • 服務(wù)號