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首頁> 外文期刊>Chest: The Journal of Circulation, Respiration and Related Systems >Sleep Pharmacotherapy for Common Sleep Disorders in Pregnancy and Lactation
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Sleep Pharmacotherapy for Common Sleep Disorders in Pregnancy and Lactation

機(jī)譯：睡眠藥物治療妊娠和哺乳期的常見睡眠障礙

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Sleep disturbances are common in pregnancy, and sleep disorders may worsen or present de novo in the course of gestation. Managing a pregnant patient is complicated by the risk of teratogenicity, pharmacokinetic changes, and the dynamic nature of pregnancy. Although nonpharmacologic interventions are likely safest, they are often ineffective, and a patient is left dealing with frustrations of the sleep disturbance, as well as the negative outcomes of poor sleep in pregnancy. As with any other condition in pregnancy, management requires an understanding of pregnancy physiology, knowledge of the impact of a given condition on pregnancy or fetal and neonatal outcomes, and an ability to weigh the risk of the exposure to an untreated, or poorly treated condition, against the risk of a given drug. In partnership with the pregnant patient or couple, options for therapy should be reviewed in the context of the impact of the condition on pregnancy and offspring outcomes, while understanding that data (positive or negative) on the impact of therapy on perinatal outcomes are lacking. This article reviews the epidemiology of sleep disorders in pregnancy, general principles of prescribing in pregnancy and lactation, and safety surrounding therapeutic options in pregnancy.
機(jī)譯：睡眠障礙在懷孕中常見，睡眠障礙可能會(huì)在妊娠過程中惡化或展示De Novo。管理懷孕的患者因致畸性，藥代動(dòng)力學(xué)變化和懷孕的動(dòng)態(tài)性而變得復(fù)雜。雖然非武裝干預(yù)很可能是最安全的，但它們通常是無效的，患者留下令人沮喪的沮喪，以及懷孕睡眠不良的負(fù)面結(jié)果。與懷孕的任何其他條件一樣，管理需要了解妊娠生理學(xué)，了解給定條件對妊娠或胎兒和新生兒結(jié)果的影響，以及權(quán)衡暴露于未經(jīng)治療或治療不良或病情惡劣的風(fēng)險(xiǎn)的能力，違反給定藥物的風(fēng)險(xiǎn)。與懷孕患者或夫婦合作，應(yīng)在懷孕和后代結(jié)果的情況下，在對妊娠和后代結(jié)果的影響的情況下，缺乏對治療對圍產(chǎn)期結(jié)果的影響的數(shù)據(jù)（正面或負(fù)面）的影響。本文審查了懷孕睡眠障礙的流行病學(xué)，妊娠妊娠和哺乳期的一般原則，以及懷孕治療方案的安全。

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