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首頁> 外文期刊>Parkinsonism & related disorders >Traditional neuropsychological correlates and reliability of the Automated Neuropsychological Assessment Metrics-4 battery for Parkinson's disease
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Traditional neuropsychological correlates and reliability of the Automated Neuropsychological Assessment Metrics-4 battery for Parkinson's disease

機譯：傳統(tǒng)神經心理學相關性和帕金森氏病自動神經心理評估指標4電池的可靠性

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Background: The Automated Neuropsychological Assessment Metrics Battery-4 for PD offers the promise of a computerized approach to cognitive assessment. Methods: To assess its utility, the ANAM4-PD was administered to 72 PD patients and 24 controls along with a traditional battery. Reliability was assessed by retesting 26 patients. Results: The Cognitive Efficiency Score (CES; a global score) exhibited high reliability (r = 0.86). Constituent variables exhibited lower reliability. The CES correlated strongly with the traditional battery global score, but displayed weaker relationships to UPDRS scores than the traditional score. Multivariate analysis of variance revealed a significant difference between the patient and control groups in ANAM4-PD performance, with three ANAM4-PD tests, Math, Tower, and Pursuit Tracking, displaying sizeable differences. In discriminant analyses these variables were as effective as the total ANAM4-PD in classifying cases designated as impaired based on traditional variables. Principal components analyses uncovered fewer factors in the ANAM4-PD relative to the traditional battery. ANAM4-PD variables correlated at higher levels with traditional motor and processing speed variables than with untimed executive, intellectual or memory variables. Conclusions: The ANAM4-PD displays high global reliability, but variable subtest reliability. The battery assesses a narrower range of cognitive functions than traditional tests, and discriminates between patients and controls less effectively. Three ANAM4-PD tests, Pursuit Tracking, Math, and Tower performed as well as the total ANAM4-PD in classifying patients as cognitively impaired. These findings could guide the refinement of the ANAM4-PD as an efficient method of screening for mild to moderate cognitive deficits in PD patients.
機譯：背景：PD的自動神經心理評估指標Battery-4有望以計算機化的方式進行認知評估。方法：為了評估其實用性，將ANAM4-PD與傳統(tǒng)電池一起施用于72例PD患者和24名對照。通過重新測試26位患者來評估可靠性。結果：認知效率評分（CES;全球評分）顯示出很高的可靠性（r = 0.86）。組成變量表現出較低的可靠性。 CES與傳統(tǒng)電池總體評分高度相關，但與UPDRS評分的關系卻比傳統(tǒng)評分弱。方差的多變量分析顯示，在患者和對照組之間，ANAM4-PD的性能存在顯著差異，通過進行三個數學，塔式和追蹤追蹤的ANAM4-PD測試，顯示出相當大的差異。在判別分析中，這些變量在根據傳統(tǒng)變量對指定為受損的病例進行分類時與總ANAM4-PD一樣有效。主成分分析發(fā)現與傳統(tǒng)電池相比，ANAM4-PD中的因??素更少。與非定時執(zhí)行，智能或記憶變量相比，ANAM4-PD變量與傳統(tǒng)電機和處理速度變量的相關程度更高。結論：ANAM4-PD顯示出較高的整體可靠性，但子測試可靠性卻可變。與傳統(tǒng)測試相比，該電池評估的認知功能范圍更窄，并且在區(qū)分患者和對照方面的效果較差。在將患者歸類為認知障礙患者方面，進行了三個ANAM4-PD測試，追蹤追蹤，數學和Tower測試以及總的ANAM4-PD測試。這些發(fā)現可以指導ANAM4-PD的改進，作為篩選PD患者中輕度至中度認知缺陷的有效方法。

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